My Last Love is a TV movie about a single mother who had been diagnosed with cancer. Her treatments aren't helping, so she decides to move with her daughter Carson, from Chicago to her home on the west coast. While there, she meets a busboy named Michael and they fall in love. In the meantime, she has several struggles dealing with Carson's reaction to her illness, her mother's over-protectiveness, and the matter of who will care for her daughter when she dies.