It's not the heart, but the hypothalamus that dictates whom we love. And in the navel of Manila, four men fall in love with one woman, Aileen. Each with a different reason: provincial boy Caloy wants a wife, widower Lando desires a whore, college student Alex finds a soulmate, and Obeng the thief longs for a companion. Each may be different, but one thing is certainly true-all of these men love Aileen with all their hypothalamus.