Born in Kanagawa Prefecture, Yoshikawa debuted as a model in August 2012 with the gravure video Aimi Yoshikawa Rising Star Debut (新星 Debut 吉川あいみ). In December 2012, her switch from mainstream modeling to adult videos (AV) was announced. She made her AV debut in January 2013 in Aimi Yoshikawa AV DEBUT. In December 2013, she was awarded best actress at SOD Awards. In 2013, Yoshikawa made her acting debut in a mainstream film in Goddotan Kiss Patience Championship - The Movie, a comedy based on the popular variety show Goddotan. In 2014, she played the main role of "Hazuki Luna" in Ai LOVE Movies! Hen, a 2014 live-action adaptation of the manga series Ikenai! Luna-sensei (“Watch-out! Luna teacher").