Darkman, who has, since the first film, devoted his life to perfecting his synthetic skin and fighting crime, is horrified to learn that his old foe, Robert G. Durant, is alive. Durant wastes no time taking control of his old business. He releases an insane weapons developer from a mental institution, and uses him to create a deadly laser weapon. Now, with the help of his disguises and inhuman strength, Darkman must forever rid the world of Durant.