From his crazy birth and baptism in a wine vat in the town of La Roca and the fatal death of his parents and beloved pet, Che Kopete moves to the capital, in search of an opportunity as a cabaret comedian. His current and quiet life is interrupted overnight, when a friend who leaves her child in care, literally dies of laughter in a crazy pharmaceutical experiment. Upon hearing this fatal news, the sister of the victim, the police lieutenant of the Gope of Curacautín, Rita Astorga,decides to investigate and do justice against those responsible, led by the cruel Dolores, and his henchmen ). Before the experiment ends with the lives of thousands of Chileans, Che Kopete, wrapped by chance in the case, ends up becoming, in his way, a true antidote against evil.