Lisa, a gambler who lives for the cards. Robert, a millionaire philanthropist, Mark (Elias Koteas), a cop reaching the end of a gruesome career. Zach, a brilliant psychiatrist. Melody, a teenager battling drug addictions. Diane, a caring nurse whose patients are the only life surrounding her. What do these six people have in common? Something connects them all - each of them is on the road to self-destruction, each is truly lost. And then, something happens: they all wake up in cells in a surreal facility, without knowing how they got there or why. Are they in denial? Are they crazy? What happened? They soon discover they are not alone, when the mysterious Jacob (Pyper-Ferguson) forces them into a disturbing experiment, during which the unwilling participants come to face disturbing truths about themselves and decide each others fate in a nerve racking game of dice.