In the back-woods of America live a very special kind of people. Friendly, decent, hard-working dirt farmers. When they accidentally drink a barrel of nuclear waste they turn into tobacco chewing, flesh eating, cannibal kinfolk from hell. Meanwhile, seven sophisticated city slickers on vacation get lost in the woods and encounter a nightmare world of these illiterate, and extremely insensitive, undead. While the tourists hikers use all their wits and courage to stay alive, more and more "down-home" types imbibe the nasty brew until Redneck Zombies are everywhere. What started as a scenic nature-hike turns into a bloodbath of dismemberment and cannibalism.