Cybill Sheridan is a 40-something actress living in Los Angeles. Past her prime and working in an industry that worships youth, Cybill has the remnants of her two failed marriages all around her. Her ex-husbands, stuntman Jeff and novelist Ira, are always hanging around, sometimes sleeping on the couch. Also present are her two daughters, a grandson, and Cybill's hysterical and slightly alcoholic best friend, Maryann.