After the success of the Hong Kong TV drama Healing Hands, Hong Kong's Television Broadcast Company, TVB filmed the second installment Healing Hands II in 2000. Following the HH1 storyline, Paul's girlfriend Jackie finally awakes after two years in a coma. Just when the audiences think the perfect couple can finally be together, fate brings Jackie away from Paul in a fire accident. On the other side, Henry, a doctor working at the accident and emergency department of the hospital gets into yet more trouble. He gets into a relationship with his colleague Dorothy, because of this, his lawyer girlfriend Annie decides to leave him.